WHAT IS A CLINICAL TRIAL?
A clinical trial is a research study that determines the safety and efficacy of a new treatment. In a clinical trial participants are assigned to receive specific interventions according to a research plan, or protocol, created by an investigator, who is often a physician. When a new product or approach is being studied, it is not known whether it will be helpful, harmful, or no different than available alternatives, so investigators determine the safety and efficacy of the intervention by measuring certain outcomes in the participants. Clinical trials can be sponsored, or funded, by pharmaceutical companies, academic medical centers, voluntary groups, and other organizations.1, 2
For more information about clinical trials, visit clinicaltrials.gov.
ImmunoGen-sponsored clinical trials include the following:
Compound: mirvetuximab soravtansine (IMGN853)
Cancer type(s): Ovarian
- FORWARD I PH3 Study of IMGN853 vs. Investigator's Choice of Chemotherapy in Women With FRα+ Adv. EOC, Primary Peritoneal or Fallopian Tube Cancer
- FORWARD II Study of IMGN853 in Comb. With Bevacizumab, Carboplatin, PLD or Pembrolizumab in Adults With FRa + Adv. EOC, Primary Peritoneal, Fallopian Tube, or Endometrial Cancer
- A Phase I, First-in-Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of IMGN853 in Adults With Ovarian Cancer and Other FOLR1-Positive Solid Tumors
Cancer type(s): Acute myeloid leukemia (AML)
- Open-label Study of IMGN779 in Adult Patients With Relapsed/Refractory CD33-positive Acute Myeloid Leukemia
Cancer type(s): Non-Hodgkin lymphoma (NHL)
- IMGN529 in Combination With Rituximab in Patients with Relapsed and/or Refractory DLBCL and Other Forms of NHL
Our partners are also conducting clinical trials with compounds using our antibody-drug conjugate technology.
If you are a patient considering participating in a clinical trial, consult with your doctor who can provide you with more information and help determine whether a clinical trial is appropriate for you.
If you are a physician or other healthcare provider, you can contact our Scientific Affairs team (firstname.lastname@example.org) for more information about our clinical trials.